According to the latest citation data from the Scopus database, we have compiled the top 5 most-cited review articles published in Intelligent Oncology in 2025. These articles focus on the deep intersection and cutting-edge applications of AI in oncology, pathology, and multi-omics, demonstrating exceptional academic impact!

Adaptive therapy has emerged as a promising strategy to delay or overcome therapeutic resistance in cancer. However, its clinical success depends on effective treatment response monitoring and prediction. In this new Perspective, Youcef Derbal proposes a novel framework that integrates mathematical modeling, control theory, and generative artificial intelligence (GenAI) to bootstrap the development and clinical deployment of treatment response prediction models in metastatic prostate cancer (mPC).

Intelligent Oncology features three papers that demonstrate how AI is already reshaping drug discovery in oncology—from target identification and resistance mechanisms to smart drug design. Here's a quick snapshot of each study.